Abstract: Fabrication of Asymmetric Polysaccharide Composite Membranes as Guided Bone Regeneration Materials

Saturday, May 24, 2025

jht

G J H B T

Global Journal of Hematology and Blood Transfusion is committed to dissemination of high-quality research related to the latest trends and advances in the field of Hematology and Blood Transfusion.

Read More

fp-IJNMR

I J N M R

International Journal of Nuclear Medicine Research provides an authoritative setting for the publication of high quality internationally-relevant research with respect to the field of Nuclear Medicine. Nuclear Medicine is crucial to early diagnosis and treatment of diseases that threaten human lives.

fp-IJGONC

I J G O N C

International journal of Gynecology, Obstetrics and Neonatal Care is a peer reviewed medical journal provides up-to-date results of basic and clinical studies in Gynecology, Obstetrics and Neonatology. The primary mission of the journal is to promote improvement in the health.

fp-IJAAPR

I J A A P R

International Journal of Advanced Applied Physics Research is a refereed and highly professional journal that publishes premium theoretical and pragmatic papers in the field of Applied Physics.

fp-IJCLPR

I J C L R

International Journal of Cardiology and Lipidology Research is a peer reviewed medical journal which strengthen the research and educational base of Cardiology and Lipidology.We publish original research articles, reviews, case studies, conference papers and short notes related to aforementioned field.

neuro

J A N R

Journal of Advanced Neuroscience Research is a peer reviewed scientific journal providing fascinating and unique forum for publishing original experimental and review articles.

Read More

oncology

W J O R

World Journal of Oncology Research is a peer-reviewed scientific journal which strengthens the research and educational base of Oncology.

Read More

clinical

J C M R U

Journal of Clinical Medicine Research Updates is an international peer reviewed journal related to latest advances in all areas of clinical medicine.

Read More

food

I J F P T

International Journal of Food Processing Technology is a peer reviewed scientific journal providing an authoritative setting for the publication of internationally-relevant research.

Read More

proteomics

J T P R

Journal of Translational Proteomics Research is a scientific journal providing a scholarly forum for novel scientific research in the field of translational proteomics.

Read More

Latest News

Latest Issue of “ International Journal of Membrane Science and Technology” has published. Visit link; “ Latest Issue" ....! Special Issue of “International Journal of Membrane Science and Technology” is scheduled for Feb-2022..! Kindly Visit link: “Special Issues for IJMST”

Journal of Advances in Biomedical Engineering and Technology (Volume 2 Issue 1)
Fabrication of Asymmetric Polysaccharide Composite Membranes as Guided Bone Regeneration Materials
Pages 51-61 Na Li, Mingyan Zhao, Bihua Ye, Lihua Li, Lu Lu, Shan Ding, Changren Zhou, Hong Li, Yanpeng Jiao and Mingxian Liu DOI: http://dx.doi.org/10.15379/2409-3394.2015.02.01.7 Published: 6 May 2015
Abstract
Periodontal regeneration can be achieved by guided tissue and guided bone regeneration (GTR/GBR) membranes, which act as a physical barrier to exclude migration of connective and epithelium, favoring the repopulation of periodontal ligament cells. Asymmetric polysaccharide GBR membranes with two different surfaces were developed in this study. Positive chitosan (CS), negative hyluronaic acid (HA) and konjac glucomannan (KGM) were composited by electrostatic interaction, forming smooth and dense membranes as upper surface to inhibit the ingrowth of cells from gingiva. The lower porous and coarse surface was obtained by gel freeze-drying and mineralization to improve the regeneration of the bone tissue. The performance of the membranes was characterized by Infrared Radiation (IR), X-ray diffraction (XRD), scanning electron microscope (SEM), tensile strength and biological evaluation. It was found that the composite membranes with chitosan content of 56.7 wt%in the dry state possess the highest tensile strength, with elongation 10 times more higher than that of the pure CS ones. Additionaly, open pores with diameter of 10-100 µm and homogenouse distributed nano-hydroxyapatite (HAP) were investigated on the coarse part. Cell studies demonstrated that the porous surface promoted the growth of the preosteoblast. Overall, the composite membranes may be useful for regeneration of periodontal regeneration.
Keywords
Periodontal regeneration, Guided bone regeneration, Chitosan, Asymmetric membrane, Mineralization.

Indexed In

CROSSREF

2co

copyrc