| Journal of Advanced Catalysis Science and Technology (Volume 3 Issue 2) | |
| Natural Hydroxyapatite Ca5(PO4)3OH: An Efficient Catalyst for the Chemo- and Regioselective Enamination of the β-Ketoesters |  |
| Pages 63-67
Abdelhadi Louroubi, Halima Ouahine, Brahim Boualy, Mustapha Ait Ali and Larbi El Firdoussi DOI: http://dx.doi.org/10.15379/2408-9834.2016.03.02.03Published: 27 October 2016 |
|
| Abstract | |
| HydroxylapatiteorhydroxyapatiteCa5(PO4)3OH (Hap), a naturalmineral speciesof the family ofphosphate,efficientlycatalyzed the condensationof 1,3-ketoesterswith primary aminesundersolvent-freeconditions. Thereaction was completein10 min, toaffordβ-enaminoestersin a high yieldand good selectivity. Moreover, the catalyst can be re-used for four times with good activities. | |
| Keywords | |
| Hydroxyapatite, Catalyst, Condensation, β-enaminoester, Solvent free. | |
 |
|