International Journal of Cardiology and Lipidology Research  (Volume 2 Issue 1)
 Effects of Physical Activity on The Inflammatory Process Related to Insulin Resistance and Obesity IJCLR-JHome
Pages 20-26

Aline Marcadenti, Francisca Mosele, Mirna Stela Ludwig, Thiago Gomes Heck and Erlon Oliveira de Abreu-Silva

Published: 21 March 2015
  Atherosclerosis, the pathophysiological substrate for cardiovascular disease (CVD), is the final stage of an inflammatory cascade. During the process, endothelial dysfunction ensues and the inflammatory state is perpetuated. A number of traditional risk factors, as obesity and insulin resistance/type 2 diabetes, are characterized by a proinflammatory state as well, with increased levels of cytokines, interleukins, vasoactive peptides and enhanced expression of specific cellular receptors. The anti-inflammatory properties of physical exercise and its positive effects as a strategy for obesity and insulin resistance have already been shown in terms of cardiovascular protection and survival.
  Inflammation, Endothelial dysfunction, Obesity, Insulin resistance, Exercise.