International Journal of Cardiology and Lipidology Research  (Volume 2 Issue 1)
 Effects of Physical Activity on The Inflammatory Process Related to Insulin Resistance and Obesity IJCLR-JHome
Pages 20-26

Aline Marcadenti, Francisca Mosele, Mirna Stela Ludwig, Thiago Gomes Heck and Erlon Oliveira de Abreu-Silva

DOI: http://dx.doi.org/10.15379/2410-2822.2015.02.01.05
Published: 21 March 2015
Abstract
  Atherosclerosis, the pathophysiological substrate for cardiovascular disease (CVD), is the final stage of an inflammatory cascade. During the process, endothelial dysfunction ensues and the inflammatory state is perpetuated. A number of traditional risk factors, as obesity and insulin resistance/type 2 diabetes, are characterized by a proinflammatory state as well, with increased levels of cytokines, interleukins, vasoactive peptides and enhanced expression of specific cellular receptors. The anti-inflammatory properties of physical exercise and its positive effects as a strategy for obesity and insulin resistance have already been shown in terms of cardiovascular protection and survival.
Keywords
  Inflammation, Endothelial dysfunction, Obesity, Insulin resistance, Exercise.
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