| Journal of Advanced Catalysis Science and Technology (Volume 1 Issue 2) | |
| One-Pot Transformation of Olefins into a-Aminoalcohols Via Vic-Bromohydrins Catalyzed by Silica |  |
| Pages 10-15 Saadia Oubaassine, Brahim Boualy, Soufiane El Houssame, Mustapha Ait Ali and Published: 24 November 2014 |
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| Abstract | |
| Commercially available silica (SiO2) was found to be highly effective catalyst for one-pot synthesis of -aminoalcohols from olefins via bromohydrins using morpholine as nitrogen fragment donor. Furthermore, silica in the presence of easily accessible N-bromosuccimide (NBS) catalyzes a rapid and quantitative room temperature bromohydroxylation of simple olefins. Various olefins are easily converted to the corresponding vic-bromohydrins and in “one pot” to -aminoalcohols in excellent yields and high selectivity. The reaction offers a simple and efficient method for the preparation of vic-bromohydrins and -aminoalcohools. | |
| Keywords | |
| Aminoalcohol, Bromohydroxylation, Morpholine, Olefins, One-pot synthesis, Silica. | |
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