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Nonalcoholic fatty liver disease (NAFLD) includes a wide spectrum of liver conditions ranging from simple steatosis to nonalcoholic steatohepatitis (NASH) and advanced hepatic fibrosis. Taking into account that NAFLD shares many common risk factors with cardiovascular diseases, it is evident that NAFLD may promote to increased cardiovascular morbidity and mortality.
Cumulative evidence suggests that NAFLD is linked to atherosclerosis, coronary artery disease, obesity, type 2 diabetes, and also predicts the clustering of risk factors for cardiovascular diseases.
To our opinion, the role of NAFLD in the prediction of cardiovascular risks should be investigated for coronary artery disease (CAD) prognosis assessment
This review focuses on the pathophysiologic relationships between NAFLD and cardiovascular diseases, subclinical and clinical cardiovascular manifestations in NAFLD. |
