Global Journal of Hematology and Blood Transfusion  (Volume 6 Issue 1)
A Case of Plasmablastic Lymphoma in an Immunocompetent Individual  Global Journal of Hematology and Blood Transfusion
Pages 6-9

P. Satya Dattatreya and Rekha Bansal

DOI: http://dx.doi.org/10.15379/2408-9877.2019.06.01.02
Published: February  2019
Abstract

Introduction: Plasmablastic Lymphoma, a subtype of Diffuse large B-cell lymphoma is known to occur in association with HIV infection. We report a case of extraoral plasmablastic lymphoma at an unusual site.

Case presentation: 66 years old male patient was evaluated in view of persistent headache and proptosis. He was found to have a frontal mass lesion extending into the orbit. Pathology and IHC confirmed it to be Plasmablastic Lymphoma. He received treatment with DA-R-EPOCH with bortezomib to which he responded extremely well and remains disease free for more than 12 months.

Conclusion: Despite being an aggressive lymphoma with poor prognosis, our patient responded extremely well to the treatment. 

Keywords
Plasmablastic lymphoma, Immunocompetent, Extraoral disease, Non-Hodgkin’s lymphomas, B-cell lymphoma.
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