Recent Advances on Modeling the Lateral Flow Immunoassay

Authors

  • Nianyin Zeng Xiamen University
  • Yurong Li Instrumentation and Pharmaceutical Technology
  • Min Du Instrumentation and Pharmaceutical Technology

Keywords:

Lateral flow immunoassay, Modeling, Convection diffusion reaction, Nonlinear state-space model, Stochastic dynamic model, Immunochromatographic assay.

Abstract

The rapid immunochromatographic test strip, also called lateral flow immunoassay (LFIA), has recently attracted considerable research attention in the past decade because of its advantages when applied to a wide variety of point-of-care (POC) tests. This paper reviewed recent advances on modeling the LFIA and summarized their advantages and limitations. It is worth mentioning that there is a growing research interest on the general modeling issue for the LFIA system. In order to optimize LFIA performance for the purpose of quantification, it is of great importance to develop a mathematical model that allows us to simulate dynamic characteristics and also find out the effects of various design parameters in a both rapid and inexpensive way.

Author Biographies

Nianyin Zeng, Xiamen University

Mechanical and Electrical Engineering

Yurong Li, Instrumentation and Pharmaceutical Technology

Fujian Key Laboratory of Medical

Min Du, Instrumentation and Pharmaceutical Technology

Fujian Key Laboratory of Medical

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Published

2015-04-30

Issue

Vol. 2 No. 1 (2015)

Section

Articles

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