F-18 FDG PET/CT in Tuberculosis: Non-Invasive Marker of Therapeutic Response to Antitubercular Therapy

Authors

  • Koramadai Karuppusamy Kamaleshwaran PET/CT and Radionulcide Therapy
  • Ajit Sugunan Shinto PET/CT and Radionulcide Therapy
  • Sudhakar Natarajan Kovai Medical Center and Hospital Limited
  • Vyshakh Mohanan PET/CT and Radionulcide Therapy

Keywords:

Tuberculosis, FDG PET/CT, ATT.

Abstract

Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) imaging, an established procedure for evaluation of malignancy, also shows increased FDG uptake in inflammatory conditions like tuberculosis. We present two patients, one renal cell carcinoma, post nephrectomy on follow up, evaluated to have cervical and mediastinal nodes diagnosed as tuberculosis and another case of disseminated tuberculosis mimicking metastasis. They were started on Anti tubercular therapy (ATT). Post 2 months treatment, FDG PET/CT showed response in most of the lesions.FDG PET/CT allows an easy evaluation of early therapeutic response in patients with TB, particularly extra-pulmonary TB.

Author Biographies

Koramadai Karuppusamy Kamaleshwaran, PET/CT and Radionulcide Therapy

Nuclear Medicine

Ajit Sugunan Shinto, PET/CT and Radionulcide Therapy

Nuclear Medicine

Sudhakar Natarajan, Kovai Medical Center and Hospital Limited

Medical oncology

Vyshakh Mohanan, PET/CT and Radionulcide Therapy

Nuclear Medicine

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Published

2015-03-20

Issue

Section

Articles