Vasculitis Diagnosed on Fluorine-18 Labelled-2-Deoxy-2-Fluoro-D-Glucose Uptake in A Patient With Fever of Unknown Origin and A History of Non Hodgkin’s Lymphoma

Authors

  • Artor Niccoli Asabella University of Bari
  • Alessandra Di Palo University of Bari
  • Corinna Altini University of Bari
  • Cristina Ferrari University of Bari
  • Nunzio Merenda University of Bari
  • Giuseppe Rubini University of Bari

Keywords:

18F-FDG PET/CT, Vessels inflammation, NHL, Takayasu arteritis, FUO.

Abstract

There are increasing data demonstrating the role of 18F-flourodeoxyglucose positron emission tomography with computerized tomography fusion (18F-FDG PET/CT) in the diagnosis of large vessel vasculitis, including Takayasu arteritis and giant cell arteritis. We report a case of large vessel vasculitis detected on 18F-FDG PET/CT; a 32-year-old woman with history of Non Hodgkin Lymphoma, admitted with fever of unknown origin (FUO) of 2-months duration and asthenia. To exclude FUO of malignancy, in the suspect of NHL relapse, 18F-FDG PET/CT imaging was performed. The images demonstrated significant 18F-FDG uptake in aortic arch and no signs of NHL relapse. This case report supports the role of 18F-FDG PET/CT as a useful and noninvasive tool in diagnostic evaluation of patient with FUO, both by excluding a malignant etiology and providing information about other possible causes such as inflammation, including vasculitis. 18F-FDG PET/CT is very useful in the early diagnosis of active inflammation including vasculitis and provides timely information for appropriate therapy.

Author Biographies

Artor Niccoli Asabella, University of Bari

Nuclear Medicine Unit – D.I.M.

Alessandra Di Palo, University of Bari

Nuclear Medicine Unit – D.I.M.

Corinna Altini, University of Bari

Nuclear Medicine Unit – D.I.M.

Cristina Ferrari, University of Bari

Nuclear Medicine Unit – D.I.M.

Nunzio Merenda, University of Bari

Nuclear Medicine Unit – D.I.M.

Giuseppe Rubini, University of Bari

Nuclear Medicine Unit – D.I.M.

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Published

2015-03-20

Issue

Vol. 2 No. 1 (2015)

Section

Articles

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