STUDY OF ANTI-INFLAMMATORY ACTIVITY OF “ORTOF-S” TABLETS

Authors

  • Yunusova Malikakhon Saidhabibovna Tashkent Medical Academy, Tashkent, Republic of Uzbekistan
  • Allayeva Munira Jurabayevna Tashkent Medical Academy, Tashkent, Republic of Uzbekistan
  • Yunusova Kholida Mannanovna Tashkent Pharmaceutical Institute, 100015, Tashkent, st. Aibek, 45, Republic of Uzbekistan
  • Jaloliddinova Muattar Shukhrat qizi Tashkent Pharmaceutical Institute, 100015, Tashkent, st. Aibek, 45, Republic of Uzbekistan
  • Anvarova Farangiz Jamshid qizi Tashkent Pharmaceutical Institute, 100015, Tashkent, st. Aibek, 45, Republic of Uzbekistan

DOI:

https://doi.org/10.15379/ijmst.v10i2.3172

Keywords:

biopharmaceutical, in vivo, solubility, quantitative determination, foreign impurities, HPLC

Abstract

The results of the study of pharmacological studies of the recommended tablets “Ortof-S” by the method “carrageenan paw edema in rats” are presented. The first stage of the study, the anti-inflammatory effect of the compared drugs “Ortof-S”, manufactured by LLC “SAMO”, Uzbekistan and “Ketaneym”, manufactured by “NEOUNIVERSE LLP”, London, UK, was studied by the method of “carrageenan paw edema in rats” anti-inflammatory activity bioavailability is to determine the solubility or release time of the drug from the medicinal forms. It was found that the solubility test characterizes the biological availability of the drug in the first approximation, since in practice there is a very frequent correlation between the rate of dissolution and absorption. The solubility, foreign impurities and the quantitative content of active substances were studied.

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Published

2023-11-21

How to Cite

[1]
Y. M. . Saidhabibovna, A. M. . Jurabayevna, Y. K. . Mannanovna, J. M. S. . qizi, and A. F. J. . qizi, “STUDY OF ANTI-INFLAMMATORY ACTIVITY OF ‘ORTOF-S’ TABLETS”, ijmst, vol. 10, no. 2, pp. 3515-3522, Nov. 2023.

Issue

Vol. 10 No. 2 (2023): Continuous publication

Section

Articles

License

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