A Non-Randomized Single-Blind Clinical Study to Assess the Utility of Strychnos Nux-Vomica L. in the Management of Patients with Bowel Disorders

Abstract

Purpose: Bowel disorders encompass a cluster of gastrointestinal conditions marked by persistent symptoms like abdominal discomfort, bloating, and changes in bowel patterns. They represent a significant public health concern necessitating increased awareness, diagnosis, and treatment efforts. This research sought to explore the potential of Nux Vomica as a treatment option for individuals suffering from bowel disorders, with the goal of reducing the frequency and intensity of their symptoms to provide optimal relief. Materials and Methods: This research involved 30 individuals diagnosed with bowel disorders according to the Rome IV diagnostic criteria. They received treatment with the homoeopathic remedy Nux Vomica, selected based on a comprehensive assessment of their symptoms. To assess the treatment's effectiveness, the study monitored a reduction in the number of symptoms and quantified improvements using the Gastrointestinal Quality of Life Index questionnaire. Results: Statistical analysis was carried out using the Student paired "t" test. Following the therapy, a significant reduction in the number of symptoms was observed, and no adverse effects were documented. On average, the GIQLI score exhibited an improvement of -38.23 ± 13.68 points (t-statistic value: 15.31), while the average decrease in the number of symptoms amounted to 4.03 ± 1.47 points (t-statistic value: 14.99). The resulting "p" value was 0.000, indicating an exceptionally low level of significance upon completion of the study. Conclusion: The homoeopathic remedy Nux Vomica effectively addresses bowel disorders. These results open up new avenues for future research exploring the treatment of bowel disorders with homeopathic medicine.