Non-Alcoholic Fatty Liver Disease as Risk of Cardiovascular Disease: Myth or Reality?

Authors

  • Hamayak Sisakian Clinic of General and Invasive Cardiology, University Hospital, Scientific-Research Center, Yerevan State Medical University
  • Ani Kocharyan Clinic of General and Invasive Cardiology, University Hospital, Scientific-Research Center, Yerevan State Medical University

Keywords:

Nonalcoholic fatty liver disease, Cardiovascular risk, Coronary artery disease, Atherosclerosis

Abstract

Nonalcoholic fatty liver disease (NAFLD) includes a wide spectrum of liver conditions ranging from simple steatosis to nonalcoholic steatohepatitis (NASH) and advanced hepatic fibrosis. Taking into account that NAFLD shares many common risk factors with cardiovascular diseases, it is evident that NAFLD may promote to increased cardiovascular morbidity and mortality.

Cumulative evidence suggests that NAFLD is linked to atherosclerosis, coronary artery disease, obesity, type 2 diabetes, and also predicts the clustering of risk factors for cardiovascular diseases.

To our opinion, the role of NAFLD in the prediction of cardiovascular risks should be investigated for coronary artery disease (CAD) prognosis assessment

This review focuses on the pathophysiologic relationships between NAFLD and cardiovascular diseases, subclinical and clinical cardiovascular manifestations in NAFLD.

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Published

2016-03-11

Issue

Vol. 3 No. 1 (2016)

Section

Articles

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